Chemist Confessions Inc.

Chemist Confessions

A Fashion & Beauty , Arts and Education podcast Explicit

#36 in Fashion & Beauty · 🇺🇸 #52 in Fashion & Beauty · 🇿🇦

About the show

Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science. The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a skincare routine, finding a serum that’ll ACTUALLY deliver, or just want to have a few laughs on some of the crazy things you see in skincare.

Newest episodes

#194) Which Prescription Retinoid Is Best For Your Acne?

Nov 11, 2026 36 min

Part 2 of our Acne episode! we break down the skincare science behind four major prescription retinoids—tretinoin, adapalene, tazarotene, and trifarotene—to help you navigate your acne treatment options. We examine how these different generations interact with specific retinoic acid receptors, evaluate key clinical data on lesion reduction and treatment success rates, and highlight why formulation design and consistent daily sun protection play a vital role in your acne journey. #skincarescience #sponsored #peptides #cosmeticchemist

#193) Why Is Treating Adult Acne So Different?

Oct 30, 2026 49 min

Why popular over-the-counter ingredients might be falling short, how prescription options like low-dose tretinoin and spironolactone fit into the picture, and what a realistic, long-term management game plan looks like for aging, irritation-prone skin. Tune in to cut through the marketing noise and get the hard science on managing adult acne! 00:00 | HOT TAKE! 02:20 | The Four Biological Culprits of Breakouts 06:50 | Age Brackets & Defining Post-Adolescent Acne 09:16 | Persistent vs. Late-Onset Acne & Lifestyle Factors 11:37 | Spotlight on The Specialist Acid Booster 15:35 | Men vs. Women: Breaking Down the Prevalence Stats 23:23 | Hormones, DHT, and Systemic Factors 31:47 | Clinical Deep Dive: Low-Dose Tretinoin Efficacy 39:04 | Modern Retinoids Beyond Tretinoin 44:42 | Hot Takes on Salicylic Acid and Azelaic Acid #skincarescience #acnecare

#192) Sheet vs. Hydrogel vs. Peel-Off Masks (and Secret Option #4!)

Oct 21, 2026 58 min

We spent three years developing our own mask tech, and it’s finally here! Meet CryoGoo, our lattice jelly peel-off mask, built to get around the material limits of traditional masks. To celebrate, we are going down a mask tech rabbit hole with everyone. In this episode,we break down what a face mask actually needs to do: occlusion, hydration, and active delivery. Then we put fabric sheet masks, bio-cellulose, hydrogel, PVA wrapping masks, and alginate modeling masks to the test, covering the real pros, cons, and performance of each. And of course, last but not least, we go through what makes our CryoGoo different from everyone else. LINKS & PRODUCTS Chemist Confessions CryoGoo Jelly Peel-Off Mask: https://chemistconfessions.com/products/cryogoo-cooling-jelly-peel-off-mask Biodance Bio-Collagen Real Deep Mask: https://go.shopmy.us/p-95630015 Revision Skincare Biocellulose Mask: https://go.shopmy.us/p-95631114 Medicube Collagen Night Wrapping Mask: https://go.shopmy.us/p-95630093 Mediheal Derma Modeling Mask: https://go.shopmy.us/p-95630988 CC Podcast Products: https://shopmy.us/collections/4698294 Shop Favorites: https://shopmy.us/chemistconfessions #skincarescience #sheetmask #cosmeticchemistry #newskincareproduct

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All episodes

#194) Which Prescription Retinoid Is Best For Your Acne?

Nov 11, 2026 36 min

#193) Why Is Treating Adult Acne So Different?

Oct 30, 2026 49 min

#192) Sheet vs. Hydrogel vs. Peel-Off Masks (and Secret Option #4!)

Oct 21, 2026 58 min

#191) Decoding Peptides with DECIEM's Rita Silva: What Does the Science Say?

Oct 9, 2026 56 min

In this special episode, we're joined by Rita Silva, Acting Director of Scientific Communications at DECIEM, for a deep dive into the science behind The Ordinary's popular peptide serums. From Multi-Peptide and Matrixyl to Argireline and the latest plant-derived growth factors, we're getting into the formulation history, clinical research, and what these products can realistically do for your skin. And of course, we have to tackle some of your biggest peptide questions. Can you mix copper peptides with vitamin C? Are peptide serums worth adding to a retinoid routine? And where should a peptide beginner even start? #skincarescience #sponsored #peptides #cosmeticchemist

#190) Chemists Test 7 CE Ferulic Dupes vs. the Original

Sep 18, 2026 36 min

PLEASE NOTE: In this episode, the original Skinceuticals CE Ferulic formula with only 15% ascorbic acid, 1% tocopherol, and 0.5% ferulic acid was tested for this episode. We dive into part two of our vitamin C series by putting popular C E Ferulic dupes to the test. Before revealing our side-by-side stability results, we go through a very helpful study from Slovenia examining 41 finished vitamin C products using HPLC testing to compare the quirks of various vitamin C derivatives—including L-ascorbic acid, ascorbyl glucoside, sodium ascorbyl phosphate, and 3-O-ethyl ascorbic acid. Then we go through our 8 week test findings of 7 CE Ferulic dupes and compare them to the mother formula from Skinceuticals. Shop our favorite C E Ferulic Dupes We've Tried Here: https://shopmy.us/collections/40252 Mentioned in Video & Liked! SKINCEUTICALS | C E Ferulic: https://go.shopmy.us/p-362235 TIMELESS SKIN CARE | 20% Vitamin C + E Ferulic Acid Serum: https://go.shopmy.us/p-362237 MAELOVE | The Glow Maker Serum: https://go.shopmy.us/p-362240 DRMTLGY | Vitamin C E + F Serum 30ml: https://go.shopmy.us/p-87127883 EDUCATED MESS | Golden Hour Gold-Stabilized Vitamin C Serum: https://go.shopmy.us/p-87128013 00:00 | Vitamin C Dupes Series Round 3 Overview 01:16 | Slovenian Study: Analyzing 41 Vitamin C Products with HPLC 06:31 | Comparing L-Ascorbic Acid Stability to the Other Vitamin C Derivatives 15:43 | Meet the Contenders: Pricing and Packaging of Popular Dupes 20:15 | Week 0 to Week 8: Accelerated Oven Stability Test Results 24:53 | Pump Disasters, Gas Buildup, and Sedimentation Issues 28:31 | pH Levels and Batch-to-Batch Consistency in Serums 33:23 | Top Affordable C E Ferulic Alternatives We Recommend 35:16 | Final Thoughts on Vitamin C Derivatives and Derivatives Wrap-Up Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #SkincarePodcast

#189) Is the updated CE Ferulic worth the $$$$?

Sep 11, 2026 43 min

We dive into a science-heavy breakdown of vitamin C formulations, focusing on the recent updates to the gold-standard C E Ferulic serum. We explore the history of L-ascorbic acid efficacy studies dating back to the 1990s by Dr. Pinnell’s lab, highlighting the classic UV-induced erythema protocol used to validate antioxidant skin protection. Then, we analyze emerging clinical data around new CE Ferulic additions: carnosine and dandelion endophytol and discuss the available data to see if the chemists can figure out whether or not this is worth the Skinceuticals price tag. 00:00 | Intro! 03:15 | L-Ascorbic Acid: A Brief Review 12:48 | What is Dandelion Endophytol? 25:00 | Carnosine's Clinical UV MED Study 29:30 | Reviewing Carnosine's Clinical Testing 34:15 | The Challenges of Plant Extracts and Actives 38:30 | Chemists discuss CE Ferulic vs. CE Ferulic 2.0 41:45 | The Chemists' Feelings on Patents

#188) We sat down with founder of Soko Glam: Charlotte Cho!

Aug 27, 2026 49 min

Check out Soko Glam: Check out our products: https://sokoglam.com/collections/chemist-confessions?_pos=1&_psq=chemist+confessions&_psid=080163648&_ss=e In celebrating our arrival on Soko Glam, we sat down with founder Charlotte Cho to dive deep into the real science, mechanics, and formulation realities behind K-Beauty. We break down the evolution of multi-step routines, the truths behind product categories like toners and essences, and why classic ingredients like snail mucin continue to hold up under scientific scrutiny. From the manufacturing hurdles of hot-pour cleansing balms to navigating US sunscreen filter regulations, we unpack what it takes to formulate effective products amidst viral TikTok trends. If you enjoyed this deep dive, don't forget to LIKE, SUBSCRIBE, and hit the notification bell 🔔 for more science-backed skincare breakdowns! #sokoglam @sokoglam #skincarescience

#187) Decoding Dr. Reju-All's PDRN & Copper Peptide #ad

Aug 21, 2026 25 min

#sponsored We’re taking a deep dive into the science behind K-Beauty brand Dr. Reju-All! In this sponsored episode, we've partnered with Dr. Reju-All, to share some of their testing behind the products: the Advanced PDRN Rejuvenating Cream and their latest launch, the Advanced PDRN Copper Peptide Serum. We discuss their PDRN ingredient sourcing and why higher concentrations aren't always better—highlighting in vitro and clinical data showing why 1,200 ppm of salmon-derived PDRN is an optimal sweet spot for barrier recovery and hydration. We also analyze their Advanced PDRN Copper Peptide Serum, exploring how encapsulating delicate copper tripeptides helps maintain formula integrity, alongside its clinical results on heat-induced skin stress, elasticity, and fine lines. Finally, we share our real-world user experience on how to layer these unique gel-gel textures into your existing routine. #rejuall #pdrn #copperpeptide • Dr. Reju-All Official Amazon Store: https://amzn.to/4gfUXI1. • Dr. Reju-All Advanced PDRN Rejuvenating Cream: https://amzn.to/4gdo4LT. • Dr. Reju-All Advanced PDRN Copper Peptide Serum: https://amzn.to/4gAJmo6. #drrejuvall #ad #pdrnserum

#186) 5 Copper Peptide Serums Tested

Aug 18, 2026 36 min

We’re cutting through the marketing fluff to decode five popular copper peptide serums! In this episode, we analyze the formulas, active ingredient combinations, and clinical data behind products from the Remedy, COSRX, Dr. Reju-All, The Ordinary, and Peach & Lily. We break down what these serums intend to treat, highlight potential formula overlap (like sneaky niacinamide and bakuchiol), and discuss the layering rules you may need to consider for your routine. Hear the chemists' perspective on where peptides fit into a smart anti-aging strategy. Timestamps 00:01 | Copper Peptide Formula Breakdown Strategy 03:00 | Remedy Copper Peptide Complex Review 06:15 | COSRX Blue Peptide Bakuchiol Serum 15:39 | Dr. Reju-All PDRN Copper Peptide Serum 19:02 | The Ordinary Multi-Peptide + Copper Peptides 21:54 | The Orindary Copper Peptide Serum's Layering Restrictions 23:33 | Peach & Lily Copper Peptide Pro Serum 26:24 | Chemists Discuss Copper Peptide Category Efficacy 31:32 | Where Peptides Fit in Your Skincare Routine #GHKCu #CopperPeptides #SkincareScience #FormulationScience #AntiAgingSkincare #SkincarePodcast #ChemistConfessions #30for30 #

#185) Are Copper Peptides (GHK-Cu) OVERRATED?

Aug 14, 2026 37 min

🧪 Is GHK-Cu Overrated? The Science of Copper Peptides Explained Are Copper Peptides (GHK-Cu) actual anti-aging powerhouses, or just smart marketing hype? In this video, we dive deep into the 50-year scientific history of GHK-Cu, breaking down the exact biological pathways behind collagen and elastin synthesis. We analyze the physiological realities of peptide size, molecular weight, and the famous 500 Dalton Rule to reveal how much of your product actually penetrates the skin barrier. And most importantly... all the theories and in vitro studies aside, what do the clinical studies REALLY say? YouTube Timestamps 00:00 | Biological Role of Copper Peptides 02:55 | The Four Categories of Skincare Peptides 04:18 | What is the 500 Dalton Rule? (Skin Permeation Guidelines) 08:32 | GHK-Cu Molecular Weight & Permeability Limitations 18:41 | Copper Peptide better than Tretinoin? What the clinical data ACTUALLY say) 25:20 | Animal Fun Fact! Copper peptides in the animal kingdom 30:58 | Can you use copper peptide with vitamin C? Active Ingredient Incompatibilities & Layering Guidelines 🔗 Resources & Links Animal fun fact study for the curious: https://www.livescience.com/bloodworms-fangs-origins Blank Slate Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser (add to cart and get the mini for free with code MINIME) Our Sunscreen Database! https://www.chemistconfessions.com/sunscreen If you enjoyed this deep dive, don't forget to LIKE, SUBSCRIBE, and hit the notification bell 🔔 for more science-backed skincare breakdowns! #GHKCu #CopperPeptides #SkincareScience #FormulationScience #AntiAgingSkincare #SkincarePodcast #ChemistConfessions #30for30 #SunscreenChallenge

#184) Are You Applying Enough Sunscreen correctly?

Aug 7, 2026 32 min

Description: We are tackling our top 10 sunscreen takeaways after four straight years of testing dozens of formulas in our 3430 series! From figuring out how much SPF you actually need to apply (and why we rating-split over the infamous Rich Area Hold Cream), we get into all the messy details. We also dive into eye-area stinging, why US mineral sunscreens hit differently, layering under makeup, handling acne flare-ups, and finding out if dropping to SPF 30 actually gives you better texture. Timestamps 00:01:05 | How Much Sunscreen Should You Actually Apply? 00:03:22 | Why Did the Rich Area Hold Cream Get a Mediocre Rating? 00:05:51 | Can You Safe Apply Sunscreen to Eyelids Without Eye Stinging? 00:09:09 | Does Rubbing Sunscreen in Too Long Ruin the Protective Film? 00:12:09 | Are US Sunscreens Inferior to International Sunscreens? 00:15:47 | How Do You Layer Sunscreen Under Makeup Without Pilling? 00:18:00 | What Is the Best Replacement for Banana Boat Light as Air? 00:20:00 | Does Sunscreen Cause Acne Breakouts? 00:20:53 | Does Lowering to SPF 30 Offer Better Texture Than SPF 50? 00:25:17 | How Do You Proper Remove Water-Resistant Sunscreen? Check out the rest of the sunscreen tested at chemistconfessions.com/sunscreen Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #skincarepodcast

#183) Testing 30 sunscreens in 30 days: US CHEMICAL SUNCREENS | Chemist Confessions Podcast

Jul 31, 2026 38 min

WE ARE BACK! Our 30 for 30 sunscreen challenge continues by diving into the wild world of US chemical sunscreens! In this episode, we break down 13 different formulas—categorized by price point from budget-friendly drugstore finds to eye-watering luxury formulas. TIMESTAMPS: 00:31 | US Chemical Sunscreens Overview 01:30 | Economical & Drugstore Sunscreens 05:11 | Neutrogena Sport Face SPF Review 07:01 | Testing Vacation Sunscreen & Pilling Issues 09:45 | Eucerin Tinted Chemical Sunscreen 13:05 | e.l.f. Suntouchable Silicone Texture 15:35 | Anua Invisible Matte & Numbuzin SPF 25:14 | Sephora & High-End Sunscreen Breakdown 28:48 | ISDIN Fusion Water Magic Performance 33:16 | Tatcha The Silken Sunscreen & Avobenzone Stability Check out the rest of the sunscreen tested at chemistconfessions.com/sunscreen Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #SkincarePodcast

#182) PART 2! 30 SUNSCREENS IN 30 DAYS! - EU and Asia

Jul 14, 2026 43 min

We are wrapping up the next leg of our #30for30 sunscreen challenge testing roundup! In this episode, we dive deep into the world of international sunscreens, putting five popular EU formulas and eight Asian sunscreens to the test. Plus, don't miss a hilarious, science-backed detour into the sophisticated culinary habits of cockatoos! Products Mentioned: • Avene Anti-Pigmentation Tinted Fluid https://go.shopmy.us/p-64086387 • La Roche Posay UVMune Tinted Fluid https://go.shopmy.us/p-67227007 • La Roche Posay UV Air Serum https://go.shopmy.us/p-71463108 • Geek & Gorgeous Zero Feel https://go.shopmy.us/p-68997384 • La Roche Posay UV Mune Hydration https://go.shopmy.us/p-67239571 • Curel Moisture Intensive Care https://go.shopmy.us/p-65141082 • Cell Fusion C Laser UV Defense https://go.shopmy.us/p-71465193 • Biore Watery Hold Cream https://go.shopmy.us/p-71465570 • Biore Rich Airy Hold Cream https://go.shopmy.us/p-71465508 • Canmake Mermaid Skin Gel Feel https://go.shopmy.us/p-71465758 • Anessa Moisture Perfect https://go.shopmy.us/p-71465924 • Rhoto Skin Aqua Hyaluronic Acid Serum https://go.shopmy.us/p-67228915 Check out the rest of the sunscreen tested at chemistconfessions.com/sunscreen Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #SkincarePodcast

#181) WE TESTED 30 SUNSCREENS IN 30 DAYS! P1 - US Sunscreen

Jul 9, 2026 22 min

The #30for30 Sunscreen Challenge is back, and we are officially kicking off our deep dive! In this episode, we’re breaking down the US mineral sunscreens we put to the test. From "accidental" foundations and heavy-duty rub-ins to luxury formulas that claim to erase wrinkles, we’re giving you the unfiltered truth on what’s worth your cash and what you should pass on. Grab your SPF, and let's get into the reviews! Timestamps 0:00 - Intro 0:45 - Missha Perfect Cover: hybrid formula that's better as a foundation than standalone sunscreen 02:15 - Merit The Uniform: A solid coverage - SPF usage rate balance 04:00 - Bloomeffects Tulip Screen Dew Drops: serious glow, $$$$$ 05:30 - CeraVe Invisible Mineral: okay daily basic, not for those in sweat-happy scenarios 07:15 - Kiehl’s Better Screen: Redness reduction & post-procedure stats 09:45 - SkinCeuticals Future Mineral: Luxury pricing vs. real anti-aging results Products Mentioned • Missha Perfect Cover BB Cream SPF 42 PA+++ ($24/50mL) go.shopmy.us/p-69775225 • Merit The Uniform Tinted SPF 45 ($38/50mL) go.shopmy.us/p-68610171 • Bloomeffects Tulip Screen Dew Drops SPF 50 ($39/30mL) go.shopmy.us/p-67231497 • CeraVe Invisible Mineral SPF 50 ($17/50mL) go.shopmy.us/p-69775395 • Kiehl’s Better Screen Miner-all UV Serum SPF 50 ($36/40mL) go.shopmy.us/p-69775593 • SkinCeuticals Future Mineral UV Defense SPF 50 ($60/50mL) go.shopmy.us/p-69775734 Check out the rest of the sunscreen tested at chemistconfessions.com/sunscreen Don't forget to like, subscribe, and drop your favorite mineral SPF in the comments! #30for30 #SunscreenChallenge #SkincarePodcast

#180) What to look for in a sunscreen?

Jun 25, 2026 56 min

Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions Instead of getting bogged down by marketing fluff, we dive deep into the real metrics of sunscreen performance: initial application speed, the science behind "watery breaks," and how a product's long-term finish affects different skin types. Listeners will walk away knowing exactly how to spot uneven film formation, navigate the nuances of water and friction resistance, and decode why certain formulas cause eye irritation or pilling so they can find their perfect, reliable daily match. #skincarescience #skincare #skincareroutine #sunscreen

#179) EWG & Yuka App Debunked!

Jun 16, 2026 51 min

Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions We are deep in sunscreen season, but unfortunately, it is also fear-mongering season. In this episode, we take a scientific look at prominent clean beauty advocacy voices like EWG and the Yuka app to untangle the science from the marketing fluff. We pull back the curtain on how these platforms analyze formulations, revealing why their extreme stances and rigid rating systems often lead to massive inconsistencies, misguided consumer fear, and ultimately, unsafe choices for your skin. By walking you through real-world formulation realities—from the stabilization challenges of zinc oxide to the actual toxicological safety profiles of chemical filters like octocrylene and vital preservatives like phenoxyethanol—we give you the context needed to tune out the noise. Tune in to ground yourself in cosmetic chemistry, find peace of mind, and gain the confidence to choose formulas that actually protect your skin daily without the unnecessary anxiety. #skincarescience #skincare #skincareroutine

#178) 5 More Tinted SPFs Tested in 2026

Jun 5, 2026 46 min

#177) We must talk about IRON OXIDES!

May 28, 2026 43 min

We are officially diving into the sunscreen segment to break down a burning, highly technical question for anyone tackling stubborn dark spots: is iron oxide a non-negotiable must-have for your hyperpigmentation routine? Sunscreen database: https://chemistconfessions.com/sunscreen Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 Shop more of my favorite products here: https://shopmy.us/chemistconfessions

#176) We tested these lineup of viral PDRN products!

May 7, 2026 35 min

We are reviewing five popular K-Beauty products to see if they actually live up to the hype. We break down the science behind different PDRN sources, explore the "50 peptides" marketing claims, and analyze clinical data to separate realistic skin improvements from clever lighting tricks. You will learn how these products perform on different skin types—from "sticky and drying" textures to clinical-grade results—so you can decide which formulas are worth your routine and which are just "science-flavored" fillers. Shop other products tested on the CC podcast here: https://shopmy.us/collections/4698294 IOPE | XMD Stem III Clinical Recovery Serum 50ml: https://go.shopmy.us/p-56645998 MEDIHEAL | PDRN Lifting Serum: https://go.shopmy.us/p-56646034 DR.REJU-ALL | Advanced PDRN Rejuvenating Cream 20ml: https://go.shopmy.us/p-56646069 REJURAN | Rejuran Turnover Ampoule C-PDRN 0.5% Renewing Serum for Smooth Texture & Glass Skin 1.01 Oz/30 mL: https://go.shopmy.us/p-56646122 NUMBUZIN | No.9 NAD+ PDRN Glow Boosting Toner: https://go.shopmy.us/p-56646193 Shop more of my favorite products here: https://shopmy.us/chemistconfessions

#175) Reviewing 2 Exosome Products!

Apr 30, 2026 45 min

We take an objective look at two polar opposite formulas—a $20 "junior" product and a $250 luxury serum—to see if the high science matches the high price tag. We break down the mysteries of sourcing, discuss why your 1% active might not be what it seems, and share our honest (and sometimes smelly) trial experiences. Whether you’re looking for genuine rejuvenation or just want to avoid lighting $500 on fire, we’ve got the data you need to navigate this rapidly changing landscape. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions #skincare #skincarescience #pdrnserum #pdrn #salmonpdrn

#174) PDRN Skincare: Longevity Cure or Just Hype?

Apr 23, 2026 39 min

Chemist Confessions Minis! https://chemistconfessions.com/shop/kits&minis We're pickup where we left off with another science update episode! Today, we're diving into another buzzy ingredient in the "longevity" space: PDRN. In this episode, we go beyond the "salmon sperm" headlines to investigate the latest science update on plant-derived PDRN from peony & rose, discuss the potential impact of molecular weight, and discuss early looks of unique PDRN delivery systems. Let's navigate the complex clinical data behind these DNA fragments and see if they actually match up to the marketing hype. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions #skincare #skincarescience #pdrnserum #pdrn #salmonpdrn

#173) How About Exosomes in Skincare Now? (A 2026 Update)

Apr 16, 2026 45 min

Exosome is that $500 buzzword that's not going anywhere anytime soon. The claims have only gotten broader from healing, skin regeneration, eczema, anti-aging, to even alopecia. In this episode, we provide an update on any new data since our last deep dive last year. We discuss how these tiny lipid nanovesicles—ranging from 30 to 200 nanometers—function as "biological mail" that triggers collagen synthesis and other regenerative pathways. But do the theories really convert to proven topical benefits? We also tackle one of the most important things you should know about exosomes - sourcing. Does it matter if your exosomes come from humans, plants, or bacteria? And what sort of skin benefits could exosomes provide...if any. Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 Check out the better oil https://chemistconfessions.com/products/the-better-oil Try our Mr. Reliable https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Check out our newly facelifted Double Play Retinol! https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions

#172) THEY CLAIM THIS WILL WORK! Reviewing Retinal products!

Apr 9, 2026 33 min

In this episode, we are diving deep into the retinal (retinaldehyde) landscape to see how current market offerings stack up. Following our technical breakdown of retinol versus retinal, we shift our focus to real-world testing of popular formulations from Krave Beauty, Prequel, Celimax, and Medik8. We examine the scientific validity of concentration ranges—from the entry-level 0.05% to the more intense 0.24%—and discuss how different textures and price points impact the user experience for various skin types. Whether you are a retinoid rookie or a seasoned pro, we provide the detailed assessment on the data to find the right one for your particular skinario. Timestamps: 00:00 - Intro 02:18 - Product Aesthetics & Textures 08:35 - Krave Beauty 24 Retinal Decode 10:21 - Prequel Retinal Renewal Decode 15:48 - Celimax Vita-A Retinal Shot Decode 22:00 - Medik8 Crystal Retinal 6 Decode 23:51 - Is Retinal 11x faster than Retinol? 28:39 - Chemists' Favorite Retinal (Personal favorites and usage recommendations) Products Mentioned: Shop everything mentioned in this video here: https://shopmy.us/collections/4698294 PREQUEL | Retinal Renew Retinaldehyde Gel: https://go.shopmy.us/p-51236222 CELIMAX | The Vita-A Retinal Shot Tightening Booster: https://go.shopmy.us/p-51236269 KRAVEBEAUTY | 24 Carrot Retinal Gentle 0 05 Retinal Serum: https://go.shopmy.us/p-51236391 MEDIK8 | Crystal Retinal 6 Serum: https://go.shopmy.us/p-51236422 (use code: CHEMISTCONFESSIONS for 15% off) Shop more of my favorite products here: https://shopmy.us/chemistconfessions

#171) We have to talk about this again: RETINOL VS RETINAL

Apr 1, 2026 36 min

We are diving back into the "rumor mill" of the retinoid world! Is Retinal actually better than Retinol, or is it just better marketing? In this episode, we revisit the Retinol vs. Retinal debate with new 2026 data. We break down what the evidence says about the retinoid conversion pathway into retinoic acid. We look at the latest clinical evidence to help you decide if it’s time to switch your anti-aging active or stay the course with your current skincare routine. Episode Timestamps 0:00 - Intro: Revisiting the Retinoid Rumor Mill 1:34 - Why Retinal (Retinaldehyde) is Growing in Popularity 2:01 - The Science of Retinoic Acid Conversion Steps 5:30 - What the Data Shows (Retinol vs. Retinal ex vivo Conversion) 9:15 - Retinal vs. Retinol: Potency & Efficacy Realities 14:40 - Is Retinal Actually Gentler? (Irritation & Skin Barrier) 18:20 - Debunking High-Concentration Retinoid Myths 23:55 - Reviewing Recent Retinal Product Launches 28:10 - How to Choose: Retinol or Retinal for your Skin Type? 36:22 - Final Verdict: Should You Switch Your Active? Resources & Mentions Retinal vs Retinol on the CC Blog: https://chemistconfessions.com/blogs/retinal-is-it-better-than-retinol Retinol vs Tretinoin: https://chemistconfessions.com/blogs/tretinoin-vs-retinol Follow us on IG : @chemist.confessions #chemistconfessions #retinal #retinol #skincarescience #antiaging #retinaldehyde #skincareroutine

#170) WE ARE ENDING THIS! Hyperpigmentation Finale!

Mar 25, 2026 24 min

We are taking a break from hyperpigmentation actives! In this finale, we tie together months of research to help you build the ultimate hyperpigmentation skincare routine. We rank the actives from our last 10 episodes—including Hydroquinone, Azelaic acid, Arbutin, Glutathione, Thiamodol, Symwhite, etc. —from S-Tier (Gold Standard) to Tier “Meh.” We also filter through the 18 products we tested down to the ones we think should be on your radar and warn you about "Niacinamide Overload." Timestamps: 0:00 - Intro: Our Hyperpigmentation Journey Recap 1:34 - How to Build a Hyperpigmentation Routine Framework 3:37 - S-Tier Actives: The Most Effective Brightening Ingredients 5:44 - A-Tier: Reliable, Well-Tested Actives for Dark Spots 7:12 - B-Tier: Decent but with some caveats 10:23 - C-Tier & "Meh" 14:17 - Top Product Recommendations: which ones should you actually try? 21:07 - The Niacinamide Math: Avoid Potential Skin Irritation from Overlayering Product Links LA ROCHE-POSAY | Mela B3 Dark Spot Serum with Melasyl + Niacinamide: https://go.shopmy.us/p-47880551 (use code: CHEMISTCONFESSIONS10 for 10% off) EUCERIN | Radiant Tone Dual Serum Dark Spot Corrector: https://go.shopmy.us/p-47881019 ULTA | The Alpha-Arbutin 2 Discoloration Care Serum: https://go.shopmy.us/p-49134844 ANUA | Azelaic Acid 10 Hyaluron Redness Soothing Serum: https://go.shopmy.us/p-49134854 PAULA'S CHOICE | 25% Vitamin C + Glutathione Clinical Serum: https://go.shopmy.us/p-49134896 Numbuzin Glutahione TXA Advanced Dark Spot Ampoule Concentrate: https://go.shopmy.us/p-49134975 Shop more of my favorite products here: https://shopmy.us/chemistconfessions

#169) Reviewing Resorcinol stuff!

Mar 17, 2026 37 min

CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We follow up our deep dive into resorcinols by featuring five specific products that highlight these key ingredients for hyperpigmentation! Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#168) Resorcinol Part 2!

Mar 12, 2026 26 min

CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation. 00:21 | Part 2: Continuing our Resorcinol Series 00:35 | What is Hexylresorcinol? 00:49 | Hexylresorcinol vs. 2% Hydroquinone: The Study Breakdown 01:07 | Testing Parameters: 1% Hexylresorcinol Concentration 01:37 | Analyzing the Results: Expert Grading and Data 01:53 | 12-Week Results: Significant Improvements in Pigmentation 02:03 | Comparing Performance to Hydroquinone 25:22 | Major Formulation Challenges with Resorcinols 25:33 | Conclusion and What’s Coming Next Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#167) Resorcinol! (But really its cousins)

Mar 10, 2026 23 min

CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation. 01:28 | What is resorcinol? 01:50 | Resorcinol in acne treatments and designer peels 02:13 | Why is resorcinol used in hair dyes? 02:33 | The shift toward resorcinol derivatives for skin safety 02:54 | EU SCC regulations on resorcinol concentrations 22:30 | Hyperpigmentation serum scenarios and skin discomfort 23:05 | Preview: Hexylresorcinol and Diamond Oil Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#166) Reviewing 5 Glutathione Products!

Feb 27, 2026 41 min

We are back for a follow-up to our glutathione deep dive! We review five specific glutathione-heavy products, four from the K-beauty world and one popular Amazon find, to see if they truly deliver on their antioxidant and brightening claims. 00:00 | Intro: Hashtags & antioxidant claims 00:24 | Welcome back to Chemist Confessions Podcast 00:30 | Glutathione deep dive follow-up 00:56 | Product lineup: 4 K-beauty + 1 Paula’s Choice 02:05 | Price points & supply differences 03:40 | Texture notes: neutral, not hydrating 05:03 | Fragrance issues & masking glutathione scent 06:05 | Stability concerns & 2-week shelf life 07:23 | Paula’s Choice texture & film discussion 08:25 | The infamous “eggy with undertone of death” scent 10:16 | Clinical claims & before/after photos skepticism 12:04 | Niacinamide + tranexamic acid doing the heavy lifting 17:57 | Tulsa Wound serum: 2% glutathione, suspicious photos 21:03 | Abib serum: percentages, encapsulation, and clinical data Product Shoutout: Double Play Retinol Face and Eye Treatment: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#165: We are finally talking about this ingredient: GLUTATHIONE!

Feb 19, 2026 34 min

WE HEARD YOU! We explore the science behind one of the most requested and hyped ingredients skincare sector: glutathione. We break down what this "master antioxidant" actually is. 01:25 | What is Glutathione? Breaking down the tri-peptide 01:54 | Why is it called the "Master Antioxidant"? 02:43 | Mechanisms: Tyrosinase inhibition and skin whitening 03:16 | The Stability Struggle: Why pH and temperature matter 06:18 | Half-life study: How quickly does it degrade in your products? 08:12 | Gold Standard Age Booster: Tactical hyperpigmentation tool 08:40 | Does it actually work? Reviewing topical clinical studies 12:35 | Study Deep Dive: 0.5% GSH vs. placebo on Indonesian women 17:36 | Oxidized Glutathione (GSSG): Is a more stable version better? Product Shoutout: Double Play Retinol Face and Eye Treatment: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#164) The Drugstore Level Alpha Arbutin Landscape

Feb 12, 2026 29 min

We explore the science of skincare as we review five affordable, drugstore-priced arbutin products. In this episode, we break down everything from texture and clinical claims and ingredient lists of popular brands to help you find the right formula for your skin. TIMESTAMPS: 01:27 | Texture Analysis: Why is Arbutin so Sticky? 03:01 | Texture Face-Off: Oily vs. Dry Skin Reactions 04:48 | Is the Beauty of Joseon Serum a Moisturizer? 06:01 | Chemist Notes: Breaking Down the Cosrx Formula 06:57 | Analyzing Clinical Claims: Inner and Outer Melanin? 09:57 | Instrumental Measurements: Reducing Dark Spots 13:01 | Deep Dive: Beauty of Joseon Ingredients 14:56 | The Truth About "Pregnancy Safe" Marketing 16:25 | The Ordinary & Naturium: Simple Serum Breakdown Product Shoutout: Double Play Retinol Face and Eye Treatment: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#163 ) The Science of Arbutin: Does It Actually Clear Dark Spots?

Feb 5, 2026 39 min

We are diving deep into the science of skincare to explore the role of Arbutin in treating hyperpigmentation. In this human conversation, we break down what exactly Arbutin is, analyze the existing data on its efficacy, and provide a comprehensive guide on what you should consider when shopping for these products. Product Shoutout: Double Play Retinol Face and Eye Treatment: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#162 ) Testing 3 Popular K-Beauty Azelaic Acid Serums

Jan 28, 2026 38 min

In this episode, we take a deep dive into the world of K-beauty azelaic acid products. We explore the science behind three popular contenders—Anua, Purito, and medicube—while decoding their ingredient lists, analyzing clinical testing data, and discussing the tricky chemistry of azelaic acid solubility. We provide a chemist’s perspective on how to choose the right formula for your skincare routine. 00:00 | Introducing K-Beauty Azelaic Acid Contenders 00:02 | The "Ouch" Factor: Testing medicube’s Needle Technology 00:04 | Sensation vs. Science: Do Spicules Improve Penetration? 00:05 | Texture Breakdown: Puridose Oil Droplets vs. Anua Watery Serum 00:08 | Decoding Ingredient Lists: Tea Tree Oil vs. Leaf Water 00:13 | Analyzing Anua’s Clinical Studies for Redness Reduction 00:18 | Is 4-Week Acne Testing Actually Meaningful? 00:23 | Bacterial Exosomes and the Future of Skincare Sourcing 00:29 | Chemist Corner: The Difficulty of Azelaic Acid Solubility 00:32 | Final Verdict: Choosing Suspensions vs. Soluble Formulas

@161) Is Azelaic Acid Better Than Hydroquinone?

Jan 19, 2026 32 min

This week, we're starting our series on hyperpigmentation answering one of the most common questions many of us will encounter which is, "Is azelaic acid better than hydroquinone for my hyperpigmentation 00:00 | Introduction: 2026 Skincare Kickoff 03:45 | Investigating the PNAS Combination Study 08:12 | Deep Dive: Azelaic Acid vs. Hydroquinone 12:50 | The Challenge of Finding Full Research Papers 18:30 | Patient Compliance: The 16-Week Milestone 22:15 | Why Visual Improvements Take Time 27:00 | Analyzing Study Abstracts vs. Full Data 31:10 | Dual Therapy Overkill: 5% Concentration Discussion 31:50 | Motivation and Routine Consistency for Results Product Shoutout: Double Play Retinol https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment Enrichment Content: Chemists’ Guide to Choosing an Exfoliating Toner https://chemistconfessions.com/blogs/how-to-choose-the-right-exfoliating-toner-for-your-skin Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next

#160) We tested 103 products in 2025

Nov 26, 2025 33 min

The Chemist Confessions podcast year-end review is here! We blitz through the 103 skincare products tested in 2025! We reveal our favorite and least favorite categories, discuss surprising finds like Hypochlorite Acid, and give our honest takes on individual products, including the Banana Boat Light as Air Sunscreen and the La Roche-Posay Cicaplast Sunscreen, and of course, Animal Corner! Timestamps: 00:00 | Welcome to Chemist Confessions Podcast & Year-End Review 01:07 | How Many Skincare Products Did We Test in 2025? (103 products!) 03:55 | Favorite Skincare Product Categories We Tested This Year 07:27 | What is Our Least Favorite Skincare Product Category? 10:07 | Why is K-Beauty C-Fu Dupe Testing Boring? 12:21 | Most Surprising Skincare Category: Cleansing Oils & Hypochlorite Acid 18:11 | Best Product of the Year: Banana Boat Light As Air Sunscreen Review 21:48 | Worst Product of the Year: La Roche-Posay Cicaplast Sunscreen Pill Test 25:54 | Most Surprising Product: What is A0X or 2X Intense? 28:17 | Are Cushion Foundations Good Sunscreens? Tarte Cushion Review Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments, and it could be feat...

#159) Occlusive Balms Head-to-Head! | Chemist Confessions Podcast

Nov 19, 2025 27 min

We did a product head-to-head comparing occlusive balms, all with a petrolatum base! Following our beef tallow deep dive, we are breaking down the texture, transfer, price, and complex chemist notes of Vaseline, Aquaphor, CeraVe, Prequel, and our own Bon Voyage. Which formula is best for sensitive, compromised, dry, or oily skin, and why a simple formula isn't always best! 00:00 | Welcome to Chemist Confessions Podcast! 00:37 | What is an occlusive balm and why does petrolatum matter? 01:09 | Vaseline vs Aquaphor: Price and ingredient breakdown 03:25 | How does Vaseline’s texture change with application amount? 06:01 | Is Aquaphor better than Vaseline for lips and transfer resistance? 07:55 | Why is CeraVe Healing Ointment less shiny than other balms? 11:31 | How do dry vs oily skin types react to occlusive balms? 14:47 | Why does Vaseline have a drug facts label? 16:07 | Should you avoid complex balm formulas for compromised skin? 23:07 | Are occlusive balms temperature sensitive? Storage tips for warmer climates Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincar...

#158) Why is BEEF TALLOW in skincare?

Nov 12, 2025 42 min

This week, we tackle one of the most requested ingredients: Beef Tallow in skincare. We break down the science, compare its characteristics to other popular ingredients like shea butter, and look at the actual topical studies (or lack thereof). 00:00 | What Is Beef Tallow and Why Is It in Skincare? 00:43 | Is Beef Tallow Really Similar to Human Skin Lipids? 02:09 | How Beef Tallow Is Made: The Science Behind the Fat 03:22 | Melting Point Breakdown: Beef Tallow vs Human Sebum 05:47 | How Extraction Methods Affect Skincare Ingredient Quality 09:37 | What Do Saponification and Iodine Values Mean for Skin? 20:25 | Does Beef Tallow Have Any Proven Skin Benefits? 37:18 | What Happened When I Put Beef Tallow on My Face? 40:56 | Shea Butter, Cocoa Butter, or Beef Tallow — What’s Best for Dry Skin? Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#157) Ceramides in products! | Chemist Confessions Podcast

Nov 3, 2025 47 min

We dive deep into the complicated science of ceramides (NP, AP, EOP) in your barrier creams, explaining the complex nomenclature and how different ceramide types function in the skin. We compare the ceramide blends found in 10 popular moisturizers and reveal the winning factors to look for when you're shopping: known percentages and clinical testing. Plus, we explore supporting ingredients like Meadowfoam Estolide and Phytosphingosine, giving you a peek behind the curtain of how these popular moisturizers are formulated. Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehacks

#156) EAST VS WEST! 10 Barrier Creams Reviewed & Ranked!

Oct 21, 2025 37 min

We review 10 popular East and West barrier creams from Aestura, Dr. Jart, Dieux, Skinceuticals, La Roche Posay, and more. We break down everything from texture and finish for different skin types to occlusives like petrolatum and dimethicone, humectants like glycerin, and clinical claims. We also look at which creams are best for "suffering" vs. generally healthy skin 00:00 | 10 Barrier Creams: East vs. West Product Lineup 02:44 | How much do Barrier Creams cost? Price Buckets 03:51 | What are the different Barrier Cream textures for dry and oily skin? 09:25 | Moisturizer Residue: How long does the cream's finish last? 16:22 | Pilling Potential: Which barrier creams are prone to pilling? 18:15 | How do chemists evaluate a barrier cream? Key ingredients 18:52 | Heavy-handed vs. Lightweight Occlusives in Barrier Creams 21:20 | Glycerin and Humectants in Barrier Creams: What position matters? 25:38 | Clinical Highlights: Dieux, Dr. Jart, and Aestura claims explained 31:17 | Barrier Cream Recommendations for Suffering vs. Healthy Skin Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #c...

#155) Sulfur Skincare Product Review | Chemist Confessions Podcast

Oct 13, 2025 16 min

We put three 10% OTC sulfur products to the test! Kate Somerville, the Ordinary, Vichy, and De La Cruz Lab have four completely different takes on sulfur. The chemists discuss which product is the best to use as an acne spot treat! Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Product Shoutout: The Specialist: https://chemistconfessions.com/products/the-specialist-exfoliating-treatment Enrichment Content: EP153: OTC Sulfur for Acne is Kinda Weird! https://www.youtube.com/watch?v=6cPB2eUtYpY&list=PLldQkxjc7bYnFkUtOw8Y07yCyBnaF4ddx&index=2 From the Blog: The Chemists’ Comprehensive Guide to Acne Pt. 1 https://chemistconfessions.com/blogs/the-chemists-comprehensive-guide-to-acne-pt-1 00:00 | Sulfur Products Review: Which 10% Sulfur Acne Treatment is Best? 00:39 | What are the selection criteria for the 4 sulfur products? 01:22 | Price comparison of The Ordinary, Vichy, Kate Somerville, and De La Cruz sulfur products 02:48 | How does a dry-skin representative use a drying sulfur spot treatment? 03:38 | Which sulfur product has a classic drying, high absorption lotion texture? 04:00 | The problem with Kate Somerville's isopropyl alcohol-based drying lotion 06:30 | Ranking sulfur products by "rotten egg smell"—which one smells the most? 08:46 | Chemist Notes: Which oil-absorbing powders are in the sulfur formulas? 11:13 | Which sulfur products contain additional acne actives like Glycolic or Salicylic Acid? 14:11 | Is sulfur a long-term preventative acne ingredient or just a spot treat? Follow us: IG: https://www.instagram.com/chemist.con... INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast...

#154) AD | A Deep Dive Into VT’s Reedle Skincare!

Oct 6, 2025 22 min

In paid partnership with VT! VT has given us insider access to the R&D behind their viral Reedle Skincare. In thanks to our community’s curiosity, they’ve decided to share the research behind their reedles, what makes them special, and all the testing they’ve done behind this product line. The chemists also share their experience and recommendation using this uniquely prickly but soothing? Kbeauty serum. Products Discussed this 2025 Podcast Season *A small portion of your purchase through these links goes to feeding a chemist. (Thank you!) https://shopmy.us/shop/collections/1280514 Enrichment Content: EP 128: Our Deep Dive into Spicules (Non-paid/non-gifted) https://www.youtube.com/watch?v=acn8V6-4_Uk&t=61s EP 129: VT’s Reedle Shot 50 vs. 100 (Non-paid/non-gifted) https://www.youtube.com/watch?v=O-BwdlFYFU0&t=1s Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#153) The Science Behind Sulfur for Acne & Skincare

Oct 1, 2025 29 min

We take a deep dive into the science behind Sulfur, a very old and historically prevalent ingredient for acne. We discuss its nonmetal clay origins and characteristic scent, often described as rotten eggs , or like "if a clay farted". The episode covers its classification as an OTC acne ingredient , its proposed catalytic and oil-absorbing mechanisms , and the challenges in its topical formulation, such as particle size. We also look at old-school research, including a study on 10% Sulfur + 4% Niacinamide drying lotion , and offer realistic expectations: Sulfur is best used as a spot treatment for quick fixes, not for long-term overall breakout reduction Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#152) MY SKIN IS ANGRY! Now what?

Sep 17, 2025 51 min

Everyone at some point in their lives will experience skin irritation. From overeager retinoid use to skin deciding to do a complete 180° just because. When skin is angry, troubleshooting your routine can start to feel stressful and overwhelming . The chemists review why skin reacts the way it does and best practices on how to appease unhappy skin and recalibrate back to your original healthy skin. Products Discussed this 2025 Podcast Season *A small portion of your purchase through these links goes to feeding a chemist. (Thank you!) https://shopmy.us/collections/1280514 Product Shoutout: Aquafix Soothing Hydrating Serum https://chemistconfessions.com/products/aquafix-hydrating-water-gel Enrichment Content: Navigating Plant Extracts: A Guide https://chemistconfessions.com/blogs/botanicals-a-skincare-ingredient-jungle EP136: Can You Just Use Water to Cleanse Your Face? https://www.youtube.com/watch?v=8GDay3OeG7Q Follow us: IG: https://www.instagram.com/chemist.confessions/ INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#151) Hypochlorous Acid Sprays Tested: Tower 28, Prequel & Magic Molecule Review!

Sep 9, 2025 30 min

We put popular hypochlorous acid sprays to the test! Tower 28, Prequel, and Magic Molecule. Do they live up to the hype for acne, redness, and barrier support? Here’s the chemists’ breakdown. Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist.* [https://shopmy.us/collections/1280514](https://shopmy.us/collections/1280514) Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist.* [https://shopmy.us/collections/1766357](https://shopmy.us/collections/1766357) Product Shoutout: Blank Slate Gentle Gel Cleanser [https://chemistconfessions.com/products/blank-slate-cleanser](https://chemistconfessions.com/products/blank-slate-cleanser) Enrichment Content: Sunscreen Layering Guide [https://www.youtube.com/watch?v=IQ0Dlb0WXvc](https://www.youtube.com/watch?v=IQ0Dlb0WXvc) Do We Absorb Sunscreen Filters into Our Bloodstreams? [https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams](https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams) Follow us: IG: / chemist.confessions INTERWEB: [https://chemistconfessions.com/](https://chemistconfessions.com/) TIKTOK: [https://www.tiktok.com/@chemistconfes](https://www.tiktok.com/@chemistconfes)... Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#150) Hypochlorous Acid Explained | Chemist Confessions Podcast

Aug 28, 2025 57 min

Hypochlorous acid is the trending skincare ingredient for acne, eczema, and irritated skin...... but does it really work? Products Discussed this 2025 Podcast Season a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514

#149) THD Products Texture Discussion | Chemist Confessions Podcast

Aug 19, 2025 27 min

From $20 drugstore finds to $185 luxury formulas, We break down Vitamin C skincare products, textures, and ingredient lists to help you choose what really works for hyperpigmentation, hydration, and beyond. Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative? https://www.youtube.com/watch?v=X9wfbFIUIJg From the Blog: Which Vitamin C Derivative is Best for My Skin https://chemistconfessions.com/blogs/which-vitamin-c-derivative-is-the-best-for-my-skin Follow us: IG: https://www.instagram.com/chemist.confessions/?hl=en INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#148) Is THD Ascorbate a worthy Vitamin C derivative?

Aug 6, 2025 26 min

Is tetrahexyldecyl ascorbate (aka. THD ascorbate) a more stable, more exciting form of vitamin C, or just another quirky chemical cousin? We unpack the science, separate facts from marketing fluff, and reveal what this ingredient really does for your skin. Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative? https://www.youtube.com/watch?v=X9wfbFIUIJg From the Blog: Which Vitamin C Derivative is Best for My Skin https://chemistconfessions.com/blogs/which-vitamin-c-derivative-is-the-best-for-my-skin Follow us: IG: https://www.instagram.com/chemist.confessions/?hl=en INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

#147) Shopping for Sunscreens in 2025! | Chemist Confessions Podcast

Jul 25, 2025 30 min

It’s the last sunscreen episode of 2025 (we promise!). The chemists have been mulling over all of the recent sunscreen drama. Ultimately, they’ve decided that the most constructive way to address everyone’s concerns is to walk everyone through how to properly shop for sunscreens in 2025. In this guided tour of sunscreens, they will also address concerns on SPF boosters and even how to process the concerning results published by Choice. 00:20 | Chemist Confessions Podcast: Addressing the Sunscreen Drama 01:00 | How to Shop for Sunscreen 01:49 | Method to Shop for Sunscreen: Addressing Concerns and Finding Confidence 02:29 | Starting Point: Chemical Fluid or Lotion Formulas 03:17 | Asian or EU Sunscreens (Chemical) 05:29 | Why are US Sunscreens Different? (Texture Discussion) 07:41 | When to Choose Mineral Sunscreens (Acne, Irritation, Sensitivity) 08:40 | Mineral Sunscreen Controversy: Are "Mineral" Sunscreens Truly Mineral? 09:58 | Understanding UV Boosters in Sunscreen Formulas 12:01 | Quirky Traits of Mineral Sunscreens: White Cast and Powdery Formulas 30 for 30 Sunscreen Challenge Compiled Summary *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357 Other products discussed this 2025 Podcast Season https://shopmy.us/collections/1280514 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Can You Layer Foundation With Sunscreen https://www.youtube.com/watch?v=IQ0Dlb0WXvc&t=1356s Chemists’ Complete Sunscreen Review Guide https://chemistconfessions.com/blogs/how-to-best-use-cleansers Follow us: IG: https://www.instagram.com/chemist.confessions/ INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes…

#146) 100 Days of Double Cleansing

Jul 16, 2025 53 min

Victoria recently decided to commit to 100 days of double cleansing on her oily, acne-prone skin. In those 100 days, she tests 10 cleansing oils and 10 gel cleansers. They discuss their likes, dislikes, and surprise discoveries amongst these formulas. Ultimately, the chemists’ goal in this experiment is to answer the question, “Should you be double cleansing every day?” Additionally, they hope that in this experiment they can help pinpoint what traits to look for in a good oil cleanser and gel cleanser. Enjoy! Products Enjoyed in the 100 Days of Double Cleansing Journey *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1942385 Other products discussed this 2025 Podcast Season https://shopmy.us/collections/1280514 Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser Enrichment Content: Chemists’ Review 5 Kbeauty Cleansing Oils https://www.youtube.com/watch?v=3WiF-LYh1no&t=380s Chemists’ Double Cleansing Guide https://chemistconfessions.com/blogs/how-to-best-use-cleansers Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes…

#145) 5 Ethyl Ascorbic Acid Products Compared

Jul 10, 2025 20 min

In this episode, we put five popular vitamin C serums featuring 3-o-ethyl ascorbic acid to the test: Beauty of Joseon Light on Serum, Elf C+E+Feruic Acid Serum, Olay Vitamin C Brightening Serum, Innisfree Green Tean Enzyme Vitamin C, and Numbuz:n 5+. This is a wild category of products. Unlike the CE Ferulic dupes, the range is far and wide in between! From texture critiques (why so sticky, Elf?) to actives breakdown, we decode the labels and share which formulas we’d choose — and which ones barely count as a vitamin C serum at all. Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514 Product Shoutout: Mr. Reliable Moisturizer with 3% Ceramide Complex https://chemistconfessions.com/products/mr-reliable-lightweight-moisturizer Enrichment Content: EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative? https://www.youtube.com/watch?v=X9wfbFIUIJg From the Blog: Which Vitamin C Derivative is Best for My Skin https://chemistconfessions.com/blogs/which-vitamin-c-derivative-is-the-best-for-my-skin Follow us: IG: https://www.instagram.com/chemist.confessions/ INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

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#194) Which Prescription Retinoid Is Best For Your Acne?

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Podcast details

Created by: Chemist Confessions Inc.
Status: Active
Latest episode: Nov 11, 2026
Episodes: 100
Release period: Weekly
Avg. episode length: 37 min
Explicit: Yes
Language: English

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