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Dr Ben O'Leary and Dr Will Ince

Deep Margin

A Medicine and Health & Fitness podcast

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About the show

Cancer coversations from the collar up; a podcast dedicated to head and neck oncology

Newest episodes

Episode 27: FLAPS: Foundations, Landmarks and Pioneers in Surgery with Professor Andrew Shache

46 min

Andrew Schache joins us - our first New Zealander but out second from the Liverpool head and neck unit. Drawing on his extensive experience, Professor Schache also reflects on the evolution of reconstructive surgery, key developments within the field, and the importance of research, education and innovation in improving patient care. Whether you are a medical student, trainee, surgeon, academic or simply interested in how surgical practice continues to develop, this episode offers an engaging and accessible insight into the past, present and future of reconstruction in surgery.

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All episodes

Episode 27: FLAPS: Foundations, Landmarks and Pioneers in Surgery with Professor Andrew Shache

46 min

Andrew Schache joins us - our first New Zealander but out second from the Liverpool head and neck unit. Drawing on his extensive experience, Professor Schache also reflects on the evolution of reconstructive surgery, key developments within the field, and the importance of research, education and innovation in improving patient care. Whether you are a medical student, trainee, surgeon, academic or simply interested in how surgical practice continues to develop, this episode offers an engaging and accessible insight into the past, present and future of reconstruction in surgery.

Episode 24: Deep Margin gets skin in the game with Neil Gross

43 min

Professor Neil Gross from MD Anderson talks us through his absolutely seminal work in the field of cutaneous SCCs and what this looks like for the head and neck community. Cemiplimab, EMPOWER, C-POST, neaodjuvant strategies - something for all the family.

Episode 23: Terry Jones talks PATHOS trial

58 min

Professor Terry Jones, Professor of Head and Neck surgery in Liverpool UK talks us throught the PATHOS trial. Pathos is Greek for "suffering," "experience," or "emotion" and he's shares his work on the trial!

Episode 18: Our man in Denmark: Jeppe Friborg talks us through DAHANCA/Vores mand i Danmark: Jeppe Friborg taler os gennem DAHANCA

38 min

The Danish Head and Neck Cancer (DAHANCA) group was established in 1976 as a working group by the Danish Society for Head and Neck Oncology. Since it has gone from strength to strength and continues to pioneer cooperative group research on a national scale! Current head Jeppe Friborg talks us through their up and coming work. Den danske gruppe for hoved- og halskræft (DAHANCA) blev etableret i 1976 som en arbejdsgruppe under Dansk Selskab for Hoved- og Halsonkologi. Siden da er gruppen gået fra styrke til styrke og fortsætter med at være pionerer inden for kooperativ gruppeforskning på nationalt plan! Nuværende leder, Jeppe Friborg, fortæller os om deres kommende arbejde.

Episode 17: Nabil Saba talks us through sinonasal cancer

50 min

Professor and Vice-chair of Hematology and Medical Oncology, and Professor of Otolaryngology at the Winship Cancer Institute at the Emory University School of Medicine in Atlanta, Georgia. He talks us through sinonasal histologies . Ben refers Will to social services.

Episode 11: Radiotherapy Revolutions with Professor Chris Nutting

37 min

Chris Nutting, Professor of Radiotherapy and leader on many pivotal trials at the ICR joins us to talk through the past 25 years of radiotherapy advances and the data underpinning these. We talk about the future and Will has some technical difficulties so there is less nonsense than usual!

Episode 10: The Rockstar talks ctDNA with Dr Glenn Hanna

53 min

Dr Glenn Hanna, Director of the Center for Cancer Therapeutic Innovation (CCTI) at Dana Faber Cancer Insitute joins us for our 10th episode and it's a cracker; Glenn talks us through the finer points of ctDNA, MRD and what the future holds for this exciting space.  

Episode 9: Salvage surgery and red lines with Vin Paleri

41 min

Professor Vin Paleri, Consultant Head and Neck Surgeon at The Royal Marsden Hospitals and Professor of Head and Neck Surgery at the Institute of Cancer Research talks us through salvage surgery data, patient selection and how to tame feral oncologists.

Episode 8: Paul Swiecicki, bispecifics and other unpronouncables!

37 min

Paul Swieciki, Associate Professor from Michigan joins us for a deep dive into bispecifics. We talk future targets, current excitiement and Ben gets excited about merchandise and a potential grudge match with friend of the show hardman Ari Rosenberg. It's a belter!

Episode 7: Immuno-radiotherapy with Swashbuckling David Sher, the node whisperer

53 min

David Sher, Medical Director of Radiation Oncology, Chief of Head and Neck Radiation Oncology Service at UT Southwestern joins us for a comprehensive discussion about radiotherapy and its interaction with the immune system. We cover SABR, perioperative trials and elective node irradiation; it's quite a journey!

Episode 1: ESMO 2025 Ari's ADCs with Ari Rosenberg

29 min

Ari Rosenberg, Assistant Professor at the University of Chicago and medical oncologist gives us his take on ADCs in head and neck cancer some of the latest data , Ben talks military strategy and Will gives fashion tips live from ESMO 2025 inBerlin!

Deep Margin has arrived!

5 min

Introductory episode explaining what to expect from the world's newest head and neck oncology podcast.

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