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Live Optimized with Jason and Priscilla Hetrick

Live Optimized

A Nutrition and Health & Fitness podcast

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About the show

Live Optimized is a weekly wellness podcast with Jason and Priscilla Hetrick. Each Monday, they break down one topic in plain language: nutrition, supplements, fitness, sleep, recovery and everyday habits. You'll learn what it is, what to ask, and how to have more informed conversations with your own healthcare provider. Made for busy people who want practical education, not jargon. New episodes every Monday. Learn more at simplyyoumed.com

Newest episodes

Hormones After 40: Why You Feel Different Even When You’re Doing Everything Right

30 min

Are you struggling with fatigue, stubborn weight gain, poor sleep, or changes in how you feel as you get older? Your hormones may be part of the picture! This week on Live Optimized, Jason and Priscilla discuss estrogen, progesterone, testosterone, perimenopause, menopause, and hormone replacement therapy. We’re breaking down how hormones influence energy, sleep, metabolism, muscle mass, and healthy aging. You’ll also learn what blood work may be helpful, the differences between hormone treatment options, and practical ways to support your health after forty. Because getting older doesn’t mean giving up on feeling your best! Live Optimized — Peptides • Wellness • Longevity For educational purposes only. Not a substitute for individualized medical advice.

Inflammation: Is Your Body Trying to Tell You Something?

29 min

Is inflammation always bad? Not necessarily! Your body actually needs inflammation to heal and protect itself. But when inflammation becomes chronic, it can affect your long-term health. This week on Live Optimized, Jason and Priscilla discuss the connection between inflammation, hormones, insulin resistance, aging, and longevity. We’re talking about anti-inflammatory nutrition, omega-3s, turmeric, vitamin D, exercise, recovery, and the importance of understanding your lab results. Plus, discover five simple ways to support your body’s natural inflammatory response. Live Optimized — Peptides • Wellness • Longevity Educational information only. Not a substitute for individualized medical advice.

Heal Your Gut: Glutamine, Probiotics, Peptides & the MTHFR Connection

32 min

Gut health is about more than digestion. Jason and Priscilla walk through nutrients and supplements people often ask about for digestive wellness. They also explain how folate metabolism and the MTHFR gene variant come into the conversation. In this episode: • What L-glutamine, probiotics and fiber supplements are, and why people ask about them • How MTHFR, folate metabolism and gut health relate, and where IV hydration and newer options fit into the discussion • Why individual needs differ, and questions to bring to your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

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All episodes

Hormones After 40: Why You Feel Different Even When You’re Doing Everything Right

30 min

Are you struggling with fatigue, stubborn weight gain, poor sleep, or changes in how you feel as you get older? Your hormones may be part of the picture! This week on Live Optimized, Jason and Priscilla discuss estrogen, progesterone, testosterone, perimenopause, menopause, and hormone replacement therapy. We’re breaking down how hormones influence energy, sleep, metabolism, muscle mass, and healthy aging. You’ll also learn what blood work may be helpful, the differences between hormone treatment options, and practical ways to support your health after forty. Because getting older doesn’t mean giving up on feeling your best! Live Optimized — Peptides • Wellness • Longevity For educational purposes only. Not a substitute for individualized medical advice.

Inflammation: Is Your Body Trying to Tell You Something?

29 min

Is inflammation always bad? Not necessarily! Your body actually needs inflammation to heal and protect itself. But when inflammation becomes chronic, it can affect your long-term health. This week on Live Optimized, Jason and Priscilla discuss the connection between inflammation, hormones, insulin resistance, aging, and longevity. We’re talking about anti-inflammatory nutrition, omega-3s, turmeric, vitamin D, exercise, recovery, and the importance of understanding your lab results. Plus, discover five simple ways to support your body’s natural inflammatory response. Live Optimized — Peptides • Wellness • Longevity Educational information only. Not a substitute for individualized medical advice.

Heal Your Gut: Glutamine, Probiotics, Peptides & the MTHFR Connection

32 min

Gut health is about more than digestion. Jason and Priscilla walk through nutrients and supplements people often ask about for digestive wellness. They also explain how folate metabolism and the MTHFR gene variant come into the conversation. In this episode: • What L-glutamine, probiotics and fiber supplements are, and why people ask about them • How MTHFR, folate metabolism and gut health relate, and where IV hydration and newer options fit into the discussion • Why individual needs differ, and questions to bring to your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Insulin Resistance: The Hidden Connection Between Energy, Cravings & Weight

33 min

Blood sugar and energy are more connected than most people realize. Jason and Priscilla explain insulin and blood sugar in simple, everyday language. They also cover how nutrition, muscle, sleep and hormones fit into metabolic health. In this episode: • What insulin does and what "insulin resistance" means • Common lab markers people discuss with their providers: fasting glucose, A1C and fasting insulin • Five everyday habits to explore, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Magnesium: The Missing Link to Better Sleep, Energy & Longevity?

25 min

Magnesium is involved in hundreds of processes in the body. Jason and Priscilla break down this essential mineral in plain, practical language. They talk about where it comes up in conversations about sleep, stress, muscle function and energy. In this episode: • The common forms of magnesium and how they differ • How magnesium and vitamin D work together • Oral vs. IV magnesium: what to know and what to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

NAC: The Antioxidant Powerhouse You’re Probably Missing

22 min

NAC is a name you'll hear more and more in wellness conversations. Jason and Priscilla explain what NAC is and how the body uses it to make glutathione, its own antioxidant. They also compare oral and IV forms and who should use caution. In this episode: • What NAC is and how it connects to glutathione • Oral vs. IV NAC and what bioavailability means • Who should use caution, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

⚡ CoQ10: The Cellular Energy Hack You’re Probably Overlooking

31 min

Your cells make energy in tiny structures called mitochondria, and CoQ10 is part of that story. Jason and Priscilla break down this naturally occurring coenzyme in plain language. They explain where it shows up in cellular energy production and antioxidant defense. In this episode: • What CoQ10 is and its role in making ATP, the energy your cells use • Why it comes up in conversations about exercise, aging and certain medications • Oral vs. injectable CoQ10, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

⚡ Running on Empty? How B-Complex Helps Power Your Energy & Metabolism

22 min

B vitamins do more than B12. Jason and Priscilla explain how the B vitamins are involved in turning food into usable energy. They also clear up why B-complex and B12 are not the same thing. In this episode: • What B1, B2, B3, B5 and B6 each do in the body • How B vitamins relate to metabolism, brain and nerve function, and muscle recovery • B-complex vs. B12, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Amino Acids: The Missing Link in Weight Loss, Muscle & Recovery

22 min

Amino acids aren't just for athletes. Jason and Priscilla break down arginine, L-carnitine, lysine and proline. They explain the roles these building blocks play in energy metabolism, circulation, collagen and muscle recovery. In this episode: • What each of these four amino acids is and where it shows up in the body • Why protein and overall nutrition matter for protecting muscle during major diet or body changes • Who may want to ask their provider about their intake, including avid exercisers Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

ALA: The Antioxidant To Recharges Other Antioxidants blood sugar + nerves + mitochondria + longevity

28 min

Alpha-lipoic acid (ALA) is an antioxidant that works alongside the body's other antioxidants. Jason and Priscilla explain what ALA is and how it works in the body. They also share why researchers are interested in it for cellular energy and healthy aging. In this episode: • What ALA is and how it relates to mitochondria and the body's antioxidant network • Areas researchers are studying, including metabolic health and nerve health • Who may want to talk with a provider first, and when ALA may not be the right choice Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Taurine Benefits: The Anti-Aging Amino Acid for Heart, Brain, Liver & Muscle Health

24 min

You've seen taurine on energy drink labels, but there's more to the story. Jason and Priscilla explain what taurine is and where it comes from. They also walk through what researchers are studying and what is still unknown. In this episode: • What taurine is, how the body uses it and where it shows up in food • Areas of research: heart, brain, liver, muscle and exercise performance • Where the evidence is still growing, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

L-Carnitine: mitochondria health, insulin resistance, energy, fitness and more!!

20 min

How does your body use the fuel it already has? Jason and Priscilla break down L-carnitine and its role in mitochondrial energy. They explain why it is more than just another supplement label. In this episode: • What L-carnitine is and how your cells use it for energy • What researchers are looking at: blood sugar regulation, exercise performance and recovery • Injectable vs. oral L-carnitine, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

💧 IV Therapy: More Than Just Hydration

29 min

An IV is more than a bag of fluids. Jason and Priscilla explain what IV infusion is and why hydration matters. They also talk about nutrients that are commonly included, such as vitamin C, B vitamins, magnesium and glutathione. In this episode: • How IV delivery differs from taking supplements by mouth • What the commonly included nutrients are and what each is involved in • Risks, who may be a candidate, who should think twice, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

SS-31 Recharge Your Cells From the Inside Out

26 min

What if the conversation about energy starts inside your cells? Jason and Priscilla explain SS-31, a peptide researchers are studying for how it interacts with mitochondria. They keep it neutral: what it is, what the research is looking at, and what is still unknown. In this episode: • What SS-31 is and how mitochondria make cellular energy • What the research is looking at, and the limits of that research • Who should be cautious, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

MOTS-C - can your body’s own mitochondria hold the key to better energy & metabolic health?

16 min

Mitochondria carry a little DNA of their own, and it makes a peptide called MOTS-c. Jason and Priscilla explain what MOTS-c is and why researchers are studying it. They also discuss potential downsides and the current limits of the research. In this episode: • What MOTS-c is and where it comes from in the body • What the research is looking at in metabolism, exercise and aging • The limits of the research, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Tirzepatide- Food noise, fat loss, and metabolic health

26 min

Tirzepatide is a prescription medication that gets a lot of attention. Jason and Priscilla explain in plain language how it works. They keep it educational and point to the conversation you would have with your own prescriber. In this episode: • What tirzepatide is and the hormone pathways it acts on (GLP-1 and GIP) • What the research is looking at, and common side effects • Questions to ask your provider, including whether it is appropriate for you Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Epithalon - can we actually slow the aging clock?

12 min

Does the science match the buzz around Epithalon? Jason and Priscilla explain what Epithalon is and why researchers are studying it. They also cover telomeres, cellular aging and the difference between lifespan and healthspan. In this episode: • What Epithalon is and what telomeres are • What the research is looking at, and why more human studies are needed • Questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

BPC-157/TB 500

17 min

Peptides are short chains of amino acids that act as signaling molecules in the body. Jason and Priscilla break down two peptides that get a lot of attention in conversations about recovery. They keep it balanced and evidence-based. In this episode: • What peptides are and how they work as signals • What the research is looking at, and where it is still early or limited to animal studies • Questions to ask your provider, and why daily habits remain the foundation Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Glutathione

20 min

Glutathione is often called the "master antioxidant." Jason and Priscilla explain what glutathione is and how the body makes it from three amino acids. They also talk about oxidative stress and what the research says. In this episode: • What glutathione is and how it works with other antioxidants like vitamins C and E • Everyday habits that relate to your body's natural glutathione production • Who should check with a provider first, and questions to ask Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

NAD+

12 min

NAD+ is found in every cell of your body, and it is one of wellness's most talked-about molecules. Jason and Priscilla explain what NAD+ is and why levels change with age. They share what current research shows and where more studies are needed. In this episode: • What NAD+ is and its role in cellular energy • Why levels change with age and what researchers are exploring • How to separate hype from evidence, and questions to ask your provider Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

Vitamin D

12 min

Vitamin D acts more like a hormone than a vitamin. In the very first Live Optimized episode, Jason and Priscilla explain why they start here. They also share their approach of looking at the whole person: sleep, food, movement, stress and labs. In this episode: • Where vitamin D comes from: sunlight, food and supplements, and why Indiana winters matter • What vitamin D is involved in, including bones and calcium, immune function and muscles • Why testing your levels and talking with your provider matter Hosts: Jason and Priscilla Hetrick. Learn more at https://simplyyoumed.com This podcast is for education only and isn't medical advice.

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